Monday, April 22, 2013

Finally, Revis a Buc (almost)

NFC Championship - San Francisco 49ers v Atlanta FalconsGetty Images

With the NFL Draft approaching, we?re taking a team-by-team look at the needs of each club. Up next is the team with the No. 30 overall selection, the Atlanta Falcons. They have a total of 11 picks, and aren?t afraid to make bold moves, so their picking somewhere north of 30 is a real possibility.

Defensive end: There?s already noise about the Falcons wanting to move up in the order, and it makes sense that their target would be a pass-rusher.

John Abraham was still producing right up until the time they released him, and they have to find someone to replace that production other than Osi Umenyiora, who has not produced at the same consistent level. If they can get into the top half of the first round, they can find someone in the Abraham mold, before the run starts.

Cornerback: This would be the other drastic need that could be the target for a move-up. It seems like forever ago they were three-deep with excellent players. But with Brent Grimes gone to Miami and and Dunta Robinson released and resurfaced in KC, they?re down to Asante Samuel and a bunch of guys.

Linebacker: You could probably run down the list of defensive positions, and the Falcons could stand to upgrade. Sean Weatherspoon is quite good, but the rest of their linebacking corps is fairly ordinary.

Tackle: The thinking is the release of Tyson Clabo opened the door for Lamar Holmes to start at right tackle, and that could work. But they still need cover here, particularly if newly rich left tackle Sam Baker goes back to the 2011 version instead of the 2012 salary-push version.

Guard: The retirement of Todd McClure leaves a big hole, but they could slide 2012 second-rounder Peter Konz over from right guard. But that leaves another vacancy. They have some in-house candidates, but need depth here.

As good as they are, they?re not as well-covered as you?d think. They have nothing to speak of in terms of depth on defense. Heck, they don?t even have a full complement of starting-caliber players on that side of the ball.

But their offensive skill-position talent is so good, it might not matter. As long as Matt Ryan, Steven Jackson, Julio Jones, Roddy White and Tony Gonzalez are together, the Falcons are going to be among the best in the NFC.

But until they get at least a little bit better on defense, it?s going to be hard for them to make the next step.

Their offseason efforts have focused on retaining their own, and making a few surgical signings of veterans who came looking for rings. Their team is good enough that 11 draft picks aren?t making their 53-man roster, so they might as well make some moves, and see if they can plug some starters in on defense.

Source: http://profootballtalk.nbcsports.com/2013/04/21/jets-most-likely-will-get-a-third-round-pick-in-2014-for-revis/related/

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Low-dose aspirin stymies proliferation of two breast cancer lines

Apr. 21, 2013 ? Regular use of low-dose aspirin may prevent the progression of breast cancer, according to results of a study by researchers at the Veterans Affairs Medical Center in Kansas City, Mo., and the University of Kansas Medical Center.

The study found that aspirin slowed the growth of breast cancer cell lines in the lab and significantly reduced the growth of tumors in mice. The age-old headache remedy also exhibits the ability to prevent tumor cells from spreading.

The lead author of the study, Gargi Maity, a postdoctoral fellow who works in the cancer research unit at the VA Medical Center, will present the team's findings on Sunday, April 21, at the annual meeting of the American Society for Biochemistry and Molecular Biology, which is being held in conjunction with the Experimental Biology 2013 conference in Boston. The senior author is Sushanta Banerjee, director of the cancer research unit and a professor at the University of Kansas Medical Center in Kansas City, Kan.

The role of aspirin, or acetylsalicylic acid, in preventing and treating cancer has intrigued researchers since the late 1980s, when an Australian study found that people who regularly used aspirin were less likely to develop colorectal cancer. Aspirin use also has been shown to reduce the risk of squamous cell esophageal cancer and prostate cancer.

Anecdotal evidence indicated that breast cancer was less likely to return in women who took aspirin to lower their risk of heart attack or stroke. But the science behind this relationship is not well understood.

The VA study found that aspirin may interfere with cancer cells' ability to find an aggressive, more primordial state. In the mouse model the researchers used, cancer cells treated with aspirin formed no or only partial stem cells, which are believed to fuel the growth and spread of tumors.

Banerjee, a professor of medicine in division of hematology and oncology, says first-line chemotherapy treatments do not destroy stem cells. Eventually, the tumor will grow again. "If you don't target the stemness, it is known you will not get any effect," he says. "It will relapse."

In lab tests, aspirin blocked the proliferation of two different breast cancer lines. One of the lines tested is often called triple-negative breast cancer, a less common but more difficult treat form of the disease. "We are mainly interested in triple negative breast cancer, because the prognosis is very poor," Banerjee says.

Triple-negative breast cancers, which will be addressed in a special thematic program at the ASBMB annual meeting, lack receptors for estrogen, progesterone and Her2. Aspirin also may improve the effectiveness of current treatments for women whose breast cancers are hormone-receptor positive. In the team's study, aspirin enhanced the effect of tamoxifen, the usual drug therapy for hormone-receptor positive breast cancer.

Aspirin is used in the treatment of a number of different conditions. Banerjee says its ability to attack multiple metabolic pathways is what makes it potentially useful in the fight against cancer. "Cancer is not a single-gene disease," he says. "Multiple genes are involved."

Aspirin is a medicine with side effects, including gastrointestinal bleeding. Researchers will continue to explore if the positive effects of regular use of the drug outweigh the risks. In 2012, the National Cancer Institute asked scientists to design studies that would illuminate the mechanisms by which aspirin and drugs with other uses appear to reduce the risk of cancer or improve the prognosis for those diagnosed with the disease. Banerjee says his lab will apply for one of the grants.

Other co-authors at the cancer research unit include Snigdha Banerjee, associate professor of medicine in hematology and oncology at KU, and postdoctoral scholars Archana De and Amlan Das.

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Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/O6RFShvmszU/130421151610.htm

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Egypt's Morsi to reshuffle Cabinet amid turmoil

CAIRO (AP) ? Egypt's President Mohammed Morsi defended his handling of some of the nation's most pressing problems in a nearly two-hour television interview on Saturday, and pledged to appoint new Cabinet ministers in a move that could ease the country's deep political polarization.

Reshuffling the Cabinet has been a key demand of the nation's largely liberal and secular opposition, which is at odds with Morsi's Islamist backers over a myriad of issues that have surfaced since the 2011 uprising that ousted longtime autocrat Hosni Mubarak.

In the interview with Al-Jazeera, Morsi said the Cabinet changes would involve a number of key ministries, although he did not say how many. He also did not give a timeline or say which ministries would be affected.

It would be the second reshuffle since Morsi took office in July. The last ministerial shake-up in January led to the appointment of a new interior minister to oversee the police force. Rights groups allege that since Mohammed Ibrahim took the post, police have used excessive force, killing dozens of people nationwide in protests against Morsi.

There is no guarantee that a reshuffle of Cabinet posts would help bridge the deepening divide between Morsi's opponents and supporters, but it could help the country build political consensus around painful austerity measures needed to secure a nearly $5 billion loan from the International Monetary Fund.

"I do these changes based on what is best for the people," Morsi said. "The aim is to fulfill what is best."

The interview aired a day after violent street clashes erupted over whether the judiciary was being allowed to act independently. It also fell on the same day that an Egyptian court ordered the release of deposed President Mubarak pending further investigation into corruption charges. He will continue to be imprisoned on two other corruption cases.

Friday's violence erupted after the president's Muslim Brotherhood backers took to the streets to call for a "cleansing" of the judiciary and for loyalists of the former regime to be purged from state institutions. Egypt's secular-minded and liberal opposition rejected their call. They deemed it a cover for upcoming measures by Morsi and the country's temporary parliament to liquidate the judiciary and infuse their own members as a means to monopolize the judicial branch.

Morsi sought to allay those fears, telling Al-Jazeera that he was among those imprisoned under Mubarak for speaking out in favor of an independent judiciary away from presidential control.

"I hear the words purging the judiciary in the framework of people's worries," he said. "This worry is from people who see recent verdicts that do not live up to their expectations."

"The acquittals of former regime figures worries people," he said. "We can appreciate this worry."

The judiciary has been a significant battleground in the political unrest that has swept Egypt. It is the sole branch of government not dominated by Morsi's Islamist allies.

On his relationship with the Brotherhood, Morsi acknowledged he once headed the group's political party and was their candidate for president.

"But the president who was elected for Egypt is the president of all Egyptians," he said, denying that the Brotherhood was running his administration from behind the scenes.

He said his administration and the opposition agree on the country's goals, but differ on the way to achieve them.

He also deflected reports that there was a rift between him and the country's powerful military, from which the past four presidents have hailed. Morsi is the first civilian and first Islamist president to be elected in the country's first free presidential race.

He said that the presidency and the army are "on the same side."

Morsi needs the military and police to help secure the country amid protests against his rule. He reported there were around 1,200 protests in February and March alone, but insisted this did not reflect waning popularity for his rule.

"Egyptians are very wise and able to know who works for them and who works against them," he said.

Morsi said he believes his popularity is growing by the day, although his opponents, including liberals, socialists and ultraconservative Islamists, contend the government is not being transparent about economic measures that could further hurt Egypt's poor. The IMF loan is linked to economic reforms.

A team from IMF left Egypt this week without broad backing from Morsi's opponents to the terms of the loan, which they said have not been made public.

The loan is seen as critical to boosting investor confidence in Egypt and freeing up around $15 billion in other international aid and investments the country desperately needs. Foreign reserves, needed to pay for vital subsidies that millions rely on for survival, stand at $13.4 billion, less than two-thirds what they were prior to the uprising.

Morsi said he will not accept conditions attached to any loan and said Egypt was not to blame for talks about the loan that have dragged on for more than a year. He said his government was acting transparently.

"There is continuous dialogue about what is best for Egyptians in the future so that we do not enter a phase that imposes price hikes and other things," he said.

Senior IMF officials say Egypt needs to restore confidence in its economy and foster political stability. IMF Managing Director Christine Lagarde said recently that "there is clearly more work to be done" regarding discussions over the loan for Egypt.

Local media have sharply criticized Morsi for his handling of the country in the 10 months he has been in office.

A number of complaints filed by Islamists and Brotherhood lawyers against media personalities have further outraged rights advocates.

Morsi said he supports freedom of the press. He said that since last year, dozens of TV stations and newspapers have been given licenses to work. He also noted that he had issued a law that bans journalists from being imprisoned for media-related charges until court verdicts are handed down.

One of the most talked about issues in the local press has been Qatar's $5 billion support package to Morsi's government and how the oil-rich Gulf state has made bids for numerous acquisitions in Egypt. There is also concern that the Palestinian Hamas group ? an offshoot of the Brotherhood that runs the Gaza Strip ? is strengthening its position in northern Sinai where Islamic militant attacks on the military and police are frequent.

Morsi, however, insisted he will not allow foreign meddling.

He has also been sharply criticized for turning to Iran to promote tourism in Egypt. Ultraconservative Sunni hard-liners have protested improving ties with the Shiite nation, particularly as it continues to support the Syrian regime against a largely Sunni Muslim opposition.

Asked if his efforts to bolster Egypt's relationship with Iran was being done to spite countries like Saudi Arabia and the United Arab Emirates for their past support of Mubarak, Morsi said he was simply working in the interest of Egyptians, and added that he supports having Iran play a role in solving the Syrian crisis.

In the wide-ranging interview, Morsi also commented on his government's relationship with the United States.

Asked why there has not yet been a bilateral meeting with President Barack Obama, Morsi said only that Egypt's relationship with Washington was "good and continuous" and built on mutual interest.

On Israel, he reiterated his respect of Egypt's peace treaty with the Israelis, and said they were working as neighbors on border security.

Turning to unrest in his own country, Morsi played down frequent clashes between Muslims and Christians, including one that led to a recent assault on a main Coptic cathedral in Cairo. He refused to characterize the clashes as sectarian violence.

Source: http://news.yahoo.com/egypts-morsi-reshuffle-cabinet-amid-turmoil-202225492.html

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Sunday, April 21, 2013

Ebert links to his Urbana home remained tight

URBANA, Ill. (AP) ? Michael Esteves wakes up every day in the spot Roger Ebert called the center of the universe, and it isn't Chicago, New York or Cannes.

Esteves owns the place, in fact. He has since 2005, when he bought the two-bedroom home in Urbana where the late movie critic grew up, writing once that it was the best possible place, the hub of it all. Since then, Esteves has gotten used to students, Ebert fans and even Asian tourists stopping by in reverence to the hometown hero who made it so big.

"People in India know about Roger Ebert," Esteves marveled.

Ebert was celebrated as a citizen of Chicago and the world after he died April 4 of cancer, but his connection with his hometown ? and the University of Illinois, his alma mater ? was strong and permanent.

Ebert donated money and more to the school, and he helped journalism students there with advice and, occasionally, connections. And he held an annual film festival in Champaign, the town next door that shares the university with Urbana. This year's version of Ebertfest goes on without him through Sunday, though his wife, Chaz Ebert, is there.

Ebert started the festival 15 years ago to showcase movies he felt were underappreciated ? some relatively new, many years old.

When Ebert died, there were no big, public displays of mourning around Champaign and Urbana. But a little like his writing, the signs were sometimes small and subtle that they hold him dear.

A sack of his favorite fast food, from Steak 'n Shake, sat among a modest handful of bouquets on the sidewalk front of the old house. You'd have to walk up close to see the small plaque embedded in the sidewalk out front, marking the spot as a landmark.

The marquee on the old Virginia Theater in Champaign ? the 92-year-old theater Ebert and his film festival helped raised money to restore ? reminded people that Ebertfest was still coming soon. Chaz Ebert emceed the opening as a tribute to her husband, and organizers say Roger Ebert left behind a long list of films that could program the festival for years to come.

And at the campus newspaper, The Daily Illini, the staff worked on a tight deadline to assemble everything it could about Ebert, a man five decades older than most of them but still tightly connected to them. He helped gather money here, too, to keep the financially strapped paper publishing. And he still proofread the program for his film festival, which the students produce every year.

Ebert was editor in chief at the Daily Illini 50 years ago. The student who holds that position now is Darshan Patel.

"To be in this chair that he once occupied, I guess it's really ? I don't know how to describe it," a clearly shaken Patel said the afternoon Ebert died. "I'm in shock ? we're in shock."

That connection to the student newspaper has inspired several current and former students.

Will Leitch, the founding editor of the sports website Deadspin and now a writer for another site, Sports on Earth, was one of them. He grew up about 45 miles south in the small town of Mattoon.

"For me personally, the idea that there was a guy who went to a high school that we played in basketball who was on television talking intelligently, and everybody knew his name, was quite a revelation," Leitch said.

His first contact with Ebert came in an email exchange in the early 1990s. An intoxicated Leitch worked up the courage late one night to ask his hero about rumors of a romantic encounter he'd had in the newsroom. Ebert issued a witty denial, and the two started a correspondence that eventually led Ebert to help Leitch find occasional work reviewing movies.

Leitch says he still has a lot of those old emails. The writing there and elsewhere says a lot about where Ebert came from, Leitch said.

"There's something inherently un-showy about where he's from, and where I'm from," Leitch said. "Put your head down, do the work, do it right ? and then go do it again. That's the way Mattoon is, and that's the way most of downstate is."

Ebert's accomplished life probably puts him at the top of the list of the most well-known people from Urbana ? but the list is a long one for a town of 41,000

After Ebert, there's fellow Illinois graduate and writer George Will. And a number of university professors, Nobel Prize winners among them. And a fictional entry, HAL, the quietly menacing computer from "2001: A Space Odyssey." In the movie he says he was assembled in Urbana.

Ebert, all his life, celebrated the place.

"The Illini were the University of Illinois, the world's greatest university, whose football stadium my father had constructed ? by himself, I believe," Ebert wrote, with a bit of exaggeration, in the same blog post in which he explained how the barbecue pit his dad built out back helped make his old home the center of all existence.

Nate Kohn is an Urbana native and University of Georgia professor who directs Ebertfest. Though the two were in school together as kids, he didn't know Ebert until they met while putting together a birthday party for HAL at the university back in the 1990s.

Urbana, Kohn says, stuck with Ebert for two reasons. One, Ebert was a creature of habit ? "He worked at one place his whole life, the Chicago Sun-Times," Kohn said.

And the other? "It was, I guess in many ways, an idyllic childhood, a classic American childhood," Kohn said.

Esteves isn't from Urbana, but he's lived there for years, moving down from Chicago and never leaving.

Since he bought Ebert's home, those occasional visitors once in a while included Ebert himself, starting with the day in 2009 when the city unveiled the plaque. After the ceremony, Ebert asked if he could come inside.

Ebert by then couldn't speak because of his long bout with cancer, but Esteves says he roamed the rooms, writing notes.

"(He said) 'Oh, I did a million dishes in here.' It was funny," Esteves said. And Ebert, he said, looked over his movie collection, heavy with super-hero flicks and movies from the 1980s.

"He was like, 'Two thumbs up!'"

___

Follow David Mercer on Twitter: www.twitter.com/davidmercerap

Source: http://news.yahoo.com/ebert-links-urbana-home-remained-tight-190059508.html

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Saturday, April 20, 2013

Facebook launches real-time graphs to highlight its data center efficiency

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Curious as to the effect that your poking wars are having on the planet? Facebook is outing power and water usage data for its Oregon and North Carolina data centers to show off its sustainability chops. The information is updated in near-real time, and the company will add its Swedish facility to the charts as soon as it's built. The stats for the Forest City, NC plant show a very efficient power usage effectiveness ratio of 1.09 -- thanks, in part, to that balmy (North) Carolina air.

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Via: GigaOm

Source: Facebook, Open Compute Project

Source: http://www.engadget.com/2013/04/19/facebook-pue-real-time-charts/

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Harman Kardon ships AVR 2700 and 3700 receivers with 4K scaling and AirPlay

Harman Kardon AVR 2700 and 3700 receivers tout both 4K scaling and AirPlay

Now that Ultra HD TVs are poised to hit the market in force, it's more important than ever to have receivers that can handle them -- even if our bank accounts often can't. Harman Kardon knows this well enough to ship its AVR 2700 and AVR 3700 receivers, both of which carry 4K passthrough and upscaling on their eight HDMI ports as a matter of course. The two also support AirPlay streaming alongside more commonplace DLNA media sharing and offer remote control mobile apps. Home theater futureproofers mostly have to decide on audio channels and network support before they buy: the $800 AVR 2700 produces 7.1-channel surround and sticks to Ethernet alone for networking, while the $996 AVR 3700 introduces 7.2-channel audio and WiFi. Few of us will use either receiver to its full potential right now, but well-heeled 4K TV owners (or just the well-prepared) can pick one up today.

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Source: Harman Kardon (1), (2)

Source: http://www.engadget.com/2013/04/20/harman-kardon-avr-2700-3700-receivers-4k-scaling-airplay/?utm_medium=feed&utm_source=Feed_Classic&utm_campaign=Engadget

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Pre-caffeine tech: Sext spam, double Doctor Whos

Our pre-caffeine roundup is a collection of the hottest, strangest, and most amusing stories of the morning.

Anonymous "brandjacked" Westboro Baptist Church on Facebook. Lots of people found it to be hilarious.

Is is any wonder Anonymous just raised $54,000 on Indiegogo launch its own news website.

Thousands Of people tweeted Rep. Mike Rogers to let him know they're Not 14, not in their basement, and they still oppose CISPA.

Yoinks! Nude sext spam hit Snapchat app users.

Twitter #Music is coming to iOS and Web, to will help you discover new tunes.

Oh! Twitter is also bringing out ads targeted to your individual tweets.

According to the American Civil Liberties Union, mobile service providers rarely provide critical security updates for Android smartphones, and the organization wants the FTC to do something about that.

Meanwhile, Microsoft is starting two-step verification for email and other services.

Why is it so hard to make a phone call in emergency situations? Let's find out.

In closing: ERMAHGERD! It's the 10th Doctor and the 11th Doctor TOGETHER AT LAST!

Compiled by Helen A.S. Popkin, who invites you to join her on Twitter and/or Facebook.

Source: http://feeds.nbcnews.com/c/35002/f/653377/s/2adfa329/l/0L0Snbcnews0N0Ctechnology0Ctechnolog0Cpre0Ecaffeine0Etech0Esext0Espam0Edouble0Edoctor0Ewhos0E1C950A5122/story01.htm

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